Nobel Prize-validated click chemistry · 3 granted patents · Free shipping on this bundle
01
Why the Full System
01. Prepare
Pre-Construction Shampoo

Clears residue and buildup that blocks the actives from penetrating. Without this step, the chemistry can’t reach the cortex.

↵ Skipping = the conditioner works on the surface instead of inside the fiber
02. Treat
Reconstruction Conditioner

Delivers Tb-0016 and Tb-0017 into the cortex where they initiate thiol-ene click reactions and begin forming new C-S covalent bonds.

↵ This is where the reconstruction happens
03. Seal
Reconstruction Leave-In

Seals the cuticle layer, locks in the new bonds, and provides ongoing protection against future thermal and chemical stress.

↵ Without sealing, reconstruction is exposed to re-damage
02
The Science

New Bonds. Not Coating.

Bleach, heat, and color break the disulfide bonds inside your hair’s cortex. Most products coat the damage or temporarily fill gaps.

ANATOMY creates new covalent C-S bonds through thiol-ene click chemistry — the same class of reactions that won the 2022 Nobel Prize in Chemistry. Molecules Tb-0016 and Tb-0017 penetrate the fiber and rebuild from the inside.

Gen 1 (2014) Olaplex Re-links broken bonds Can only reconnect what exists
Gen 2 (2020) K18 Peptide gap-filling Fills, doesn’t structurally rebuild
Gen 3 (2024) ANATOMY® Creates new covalent bonds
Explore the full science →
Tensile Strength
15.2 cN → 35.8 cN
135% increase
Bis-Adduct Formation
New covalent bonds inside fiber
81.5%
E-Modulus Reduction
vs ~5.8% for market leader
~15%
Cortex Penetration
Not surface — inside the fiber
90% hair volume
Patents
Click chemistry for hair
3 granted
Tested By
Hamburg, Germany · Independent
SGS Proderm
03
Reviews
4.8
Rated 4.8 out of 5 stars
Based on 765 reviews
Total 5 star reviews: 623 Total 4 star reviews: 117 Total 3 star reviews: 17 Total 2 star reviews: 6 Total 1 star reviews: 2
97%would recommend this product
Slide 1 selected
765 reviews
  • Rated 5 out of 5 stars
    4 months ago
    Hair anatomy

    Excellent product

    DB
    Debra B.
    Verified Buyer
  • Rated 5 out of 5 stars
    7 months ago
    Works like magic

    I'm older and going through menopause. My hair has been thinning and is damaged from years of highlights.

    I've used this 4 times. It has transformed my hair. It's much thicker and soft.

    KM
    katrina m.
    Verified Buyer
  • Rated 5 out of 5 stars
    7 months ago
    Texture Improvement

    Texture has improved and hair appears fuller after just 3 applications

    MM
    marie m.
    Verified Buyer
  • Rated 5 out of 5 stars
    8 months ago
    So far so good

    I have seen an immense improvement in my hair Thank you!

    JS
    Jill S.
    Verified Buyer
  • Rated 5 out of 5 stars
    1 year ago
    Seems to be working

    So far it seems to be working

    CH
    Cindy H.
    Verified Buyer
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04
The Protocol

How to use the Full Reconstruction System

Three steps. Ten minutes. Complete structural repair.

Step 1
Prepare
Wet hair. Apply Pre-Construction Shampoo to scalp and lengths. Massage 60 seconds. Rinse completely. (~2 min)
Step 2
Treat
Apply Reconstruction Conditioner mid-lengths to ends. Wait 3–5 minutes. This is when the click chemistry activates. Rinse. (3–5 min)
Step 3
Seal
Towel-dry. Apply Leave-In mid-lengths to ends. Do not rinse. Style as usual. (~1 min)
Total protocol: 6–8 minutes · Every wash · All hair types

Frequently Asked Questions

Full Protocol

Reconstruct. Don’t Just Repair.

Shampoo 250ml + Conditioner 150ml + Leave-In 200ml

$169.00
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